Dr. James Guest, MD, Ph.D., FAANS, is a Professor of Neurological Surgery at the University of Miami and The Miami Project to Cure Paralysis. He has been conducting research in spinal cord injury for 30 years since becoming interested during medical school and in his neurosurgery residency at the University of British Columbia. He earned his MD from the University of Alberta and his Ph.D. in Neuroscience from the University of Miami. His PhD was mentored by Richard and Mary Bunge, in which he studied the transplantation of cells for repair of the spinal cord, and the chronic neuropathology of SCI. He is certified by the Neurosurgical Boards in Canada and the US, and he completed advanced training in spinal surgery at the Barrow Neurological Institute. His research translates from late-stage preclinical models to pivotal clinical trials, focusing on neuroprotection, axonal regeneration, neuroplasticity, rehabilitation, deep brain, epidural and transcutaneous neuromodulation. He has received funding from the US Department of Defense, NIH, the State of Florida, and others. He serves leadership roles in the Reeve Foundation and Spinal Research UK and is a long-standing GWG member with the California Institute for Regenerative Medicine. Dr. Guest is Co-Chair of the North American Clinical Trials Network, the largest neurosurgical consortium for acute SCI. He has participated in multiple clinical trials in spinal cord injury, including studies on neuroprotection, cell therapy, biologics, and neuromodulation.