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Workshop 13

Tracks
Breakout 2
Saturday, October 10, 2026
2:15 PM - 3:30 PM

Overview

Epidural Spinal Stimulation for Respiratory Recovery After SCI in Humans


Details

This instructional course will review respiratory dysfunction after cervical SCI and the limitations of current treatments, including ventilation and diaphragm pacing. It will then present the mechanistic rationale for cervical epidural spinal stimulation, including closed-loop, respiration-synchronized approaches shown in preclinical models. The final segment will discuss first-in-human feasibility data on phrenic motor pool mapping, stimulation optimization, and translational trial design for restoring respiratory function.


Presenter (only the submitting author is listed below; co-presenters, where applicable, will be listed in the conference app)

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Dr Dimitry Sayenko
Associate Professor
Houston Methodist

Epidural Spinal Stimulation for Respiratory Recovery After SCI in Humans

Biography

Dr. Dimitry Sayenko earned his MD from the Russian State Medical University in 1996. From 1996 to 2006, he was a researcher at the Institute for Biomedical Problems, Russia’s leading center for biomedical research in human spaceflight. He received a PhD in Aerospace Medicine in 2005 for his work on the effects of microgravity on postural control in cosmonauts and astronauts. Dr. Sayenko completed postdoctoral training at the National Rehabilitation Center in Japan (2006-2008) and the Toronto Rehabilitation Institute in Canada (2008-2012). He subsequently held faculty appointments at the University of Louisville/Frazier Rehab Institute (2012-2014), studying mechanisms of neuromodulation induced by epidural spinal stimulation, and at UCLA (2014-2018), where he investigated spinal stimulation approaches for sensorimotor recovery after spinal cord injury. He is currently at the Houston Methodist Research Institute, where his research focuses on the neurophysiological mechanisms, parameter-dependent effects, and clinical translation of both invasive and non-invasive spinal neuromodulation to restore upper- and lower-limb motor and autonomic function after neurological injury, including spinal cord injury.
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